# 2022

#### July 2021 - June 2022

<div id="bkmrk-batot%2C-g.%2C-metcalf%2C-">1. Batot, G., Metcalf, C., Bell, L., Pauletti, A., Wilcox, K., &amp; Bröer, S. (2022). A Model for Epilepsy of Infectious Etiology using Theiler’s Murine Encephalomyelitis Virus. *Journal of Visualized Experiments*. [https://doi.org/10.3791/63673](https://doi.org/10.3791/63673)
2. Cho, J. M., Park, S.-K., Kwon, O. S., La Salle, D. T., Cerbie, J., Fermoyle, C. C., Morgan, D., Nelson, A., Bledsoe, A., Bharath, L. P., Tandar, M., Kunapuli, S. P., Richardson, R. S., Anandh Babu, P. V., Mookherjee, S., Kishore, B. K., Wang, F., Yang, T., Boudina, S., … Symons, J. D. (2022). Activating P2Y1 receptors improves function in arteries with repressed autophagy. *Cardiovascular Research*, cvac061. [https://doi.org/10.1093/cvr/cvac061](https://doi.org/10.1093/cvr/cvac061)
3. Fadul, J., Zulueta-Coarasa, T., Slattum, G. M., Redd, N. M., Jin, M. F., Redd, M. J., Daetwyler, S., Hedeen, D., Huisken, J., &amp; Rosenblatt, J. (2021). KRas-transformed epithelia cells invade and partially dedifferentiate by basal cell extrusion. *Nature Communications*, *12*(1), Article 1. [https://doi.org/10.1038/s41467-021-27513-z](https://doi.org/10.1038/s41467-021-27513-z)
4. Falekun, S., Sepulveda, J., Jami-Alahmadi, Y., Park, H., Wohlschlegel, J. A., &amp; Sigala, P. A. (2021). Divergent acyl carrier protein decouples mitochondrial Fe-S cluster biogenesis from fatty acid synthesis in malaria parasites. *eLife*, *10*, e71636. [https://doi.org/10.7554/eLife.71636](https://doi.org/10.7554/eLife.71636)
5. Ferrara, P. J., Verkerke, A. R. P., Maschek, J. A., Shahtout, J. L., Siripoksup, P., Eshima, H., Johnson, J. M., Petrocelli, J. J., Mahmassani, Z. S., Green, T. D., McClung, J. M., Cox, J. E., Drummond, M. J., &amp; Funai, K. (2021). Low lysophosphatidylcholine induces skeletal muscle myopathy that is aggravated by high-fat diet feeding. *The FASEB Journal*, *35*(10), e21867. [https://doi.org/10.1096/fj.202101104R](https://doi.org/10.1096/fj.202101104R)
6. Figueroa, K., Anderson, C. J., Paul, S., Dansithong, W., Gandelman, M., Scoles, D. R., &amp; Pulst, S. M. (2022). *Slc9a6 mutation causes Purkinje cell loss and ataxia in the shaker rat* \[Preprint\]. Neuroscience. [https://doi.org/10.1101/2022.03.28.486143](https://doi.org/10.1101/2022.03.28.486143)
7. Fix, D. K., Ekiz, H. A., Petrocelli, J. J., Mckenzie, A. M., Mahmassani, Z. S., O’Connell, R. M., &amp; Drummond, M. J. (2021). Disrupted macrophage metabolic reprogramming in aged soleus muscle during early recovery following disuse atrophy. *Aging Cell*, *20*(9). [https://doi.org/10.1111/acel.13448](https://doi.org/10.1111/acel.13448)
8. Fix, D. K., Mahmassani, Z. S., Petrocelli, J. J., de Hart, N. M. M. P., Ferrara, P. J., Painter, J. S., Nistor, G., Lane, T. E., Keirstead, H. S., &amp; Drummond, M. J. (2021). Reversal of deficits in aged skeletal muscle during disuse and recovery in response to treatment with a secrotome product derived from partially differentiated human pluripotent stem cells. *GeroScience*, *43*(6), 2635–2652. [https://doi.org/10.1007/s11357-021-00423-0](https://doi.org/10.1007/s11357-021-00423-0)
9. Guillen, K. P., Fujita, M., Butterfield, A. J., Scherer, S. D., Bailey, M. H., Chu, Z., DeRose, Y. S., Zhao, L., Cortes-Sanchez, E., Yang, C.-H., Toner, J., Wang, G., Qiao, Y., Huang, X., Greenland, J. A., Vahrenkamp, J. M., Lum, D. H., Factor, R. E., Nelson, E. W., … Welm, A. L. (2022). A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology. *Nature Cancer*, *3*(2), Article 2. [https://doi.org/10.1038/s43018-022-00337-6](https://doi.org/10.1038/s43018-022-00337-6)
10. Happ, J. T., Arveseth, C. D., Bruystens, J., Bertinetti, D., Nelson, I. B., Olivieri, C., Hedeen, D. S., Zhu, J.-F., Capener, J. L., Bröckel, J. W., Vu, L., King, C. C., Ruiz-Perez, V. L., Veglia, G., Herberg, F. W., Taylor, S. S., &amp; Myers, B. R. (2021). *A PKA Inhibitor Motif within Smoothened Controls Hedgehog Signal Transduction*. bioRxiv. [https://doi.org/10.1101/2021.07.05.451193](https://doi.org/10.1101/2021.07.05.451193)
11. Hill, J. H., Massaquoi, M. S., Sweeney, E. G., Wall, E. S., Jahl, P., Bell, R., Kallio, K., Derrick, D., Murtaugh, L. C., Parthasarathy, R., Remington, S. J., Round, J. L., &amp; Guillemin, K. (2022). *A microbiota membrane disrupter disseminates to the pancreas and increases β-cell mass* (p. 2022.03.24.485696). bioRxiv. [https://doi.org/10.1101/2022.03.24.485696](https://doi.org/10.1101/2022.03.24.485696)
12. Ingram, K., Samson, S. C., Zewdu, R., Zitnay, R. G., Snyder, E. L., &amp; Mendoza, M. C. (2022). NKX2-1 controls lung cancer progression by inducing DUSP6 to dampen ERK activity. *Oncogene*, *41*(2), Article 2. [https://doi.org/10.1038/s41388-021-02076-x](https://doi.org/10.1038/s41388-021-02076-x)
13. Jensen, O., Trivedi, S., Meier, J. D., Fairfax, K. C., Hale, J. S., &amp; Leung, D. T. (2022). A subset of follicular helper-like MAIT cells can provide B cell help and support antibody production in the mucosa. *Science Immunology*, *7*(67), eabe8931. [https://doi.org/10.1126/sciimmunol.abe8931](https://doi.org/10.1126/sciimmunol.abe8931)
14. Kaur, K., Mohammadpour, R., Ghandehari, H., Reilly, C. A., Paine, R., &amp; Kelly, K. E. (2022). Effect of combustion particle morphology on biological responses in a Co-culture of human lung and macrophage cells. *Atmospheric Environment*, *284*, 119194. [https://doi.org/10.1016/j.atmosenv.2022.119194](https://doi.org/10.1016/j.atmosenv.2022.119194)
15. Kaur, K., Mohammadpour, R., Sturrock, A., Ghandehari, H., Reilly, C., Paine, R., &amp; Kelly, K. E. (2022). Comparison of biological responses between submerged, pseudo-air-liquid interface, and air-liquid interface exposure of A549 and differentiated THP-1 co-cultures to combustion-derived particles. *Journal of Environmental Science and Health, Part A*, *57*(7), 540–551. [https://doi.org/10.1080/10934529.2022.2083429](https://doi.org/10.1080/10934529.2022.2083429)
16. Kursel, L. E., Cope, H. D., &amp; Rog, O. (2021). Unconventional conservation reveals structure-function relationships in the synaptonemal complex. *eLife*, *10*, e72061. [https://doi.org/10.7554/eLife.72061](https://doi.org/10.7554/eLife.72061)
17. LaBelle, S. A., Dinkins, S. S., Hoying, J. B., Budko, E. V., Rauff, A., Strobel, H. A., Lin, A. H., &amp; Weiss, J. A. (2022). Matrix anisotropy promotes angiogenesis in a density-dependent manner. *American Journal of Physiology-Heart and Circulatory Physiology*, *322*(5), H806–H818. [https://doi.org/10.1152/ajpheart.00072.2022](https://doi.org/10.1152/ajpheart.00072.2022)
18. Lai, S.-C. A., Gundlapalli, H., Ekiz, H. A., Jiang, A., Fernandez, E., &amp; Welm, A. L. (2021). Blocking Short-Form Ron Eliminates Breast Cancer Metastases through Accumulation of Stem-Like CD4+ T Cells That Subvert Immunosuppression. *Cancer Discovery*, *11*(12), 3178–3197. [https://doi.org/10.1158/2159-8290.CD-20-1172](https://doi.org/10.1158/2159-8290.CD-20-1172)
19. Lam, G., Beebe, K., &amp; Thummel, C. S. (2022). A direct-drive GFP reporter for studies of tracheal development in Drosophila. *Fly*, *16*(1), 105–110. [https://doi.org/10.1080/19336934.2022.2030191](https://doi.org/10.1080/19336934.2022.2030191)
20. Lin, Y., Perovanovic, J., Kong, Y., Igyarto, B. Z., Zurawski, S., Tantin, D., Zurawski, G., Bettini, M., &amp; Bettini, M. L. (2022). Antibody-Mediated Targeting of a Hybrid-Insulin-Peptide Towards Neonatal Thymic Langerin+ Cells Enhances T Cell Central Tolerance and Delays Autoimmune Diabetes. *Diabetes*, db211069. [https://doi.org/10.2337/db21-1069](https://doi.org/10.2337/db21-1069)
21. Liu, H., Gordon, S. G., &amp; Rog, O. (2021). Heterologous synapsis in C. elegans is regulated by meiotic double-strand breaks and crossovers. *Chromosoma*, *130*(4), 237–250. [https://doi.org/10.1007/s00412-021-00763-y](https://doi.org/10.1007/s00412-021-00763-y)
22. Marchetti, M., Zhang, C., &amp; Edgar, B. A. (2021). *An improved organ explant culture method reveals stem cell lineage dynamics in the adult Drosophila intestine*. bioRxiv. [https://doi.org/10.1101/2021.12.17.473114](https://doi.org/10.1101/2021.12.17.473114)
23. Mathew, B., Aoyagi, K. L., &amp; Fisher, M. A. (2021). *Yersinia pestis* Lipopolysaccharide Remodeling Confers Resistance to a *Xenopsylla cheopis* Cecropin. *ACS Infectious Diseases*, *7*(8), 2536–2545. [https://doi.org/10.1021/acsinfecdis.1c00275](https://doi.org/10.1021/acsinfecdis.1c00275)
24. McKenzie, A. I., Mahmassani, Z. S., Petrocelli, J. J., de Hart, N. M. M. P., Fix, D. K., Ferrara, P. J., LaStayo, P. C., Marcus, R. L., Rondina, M. T., Summers, S. A., Johnson, J. M., Trinity, J. D., Funai, K., &amp; Drummond, M. J. (2022). Short-term exposure to a clinical dose of metformin increases skeletal muscle mitochondrial H2O2 emission and production in healthy, older adults: A randomized controlled trial. *Experimental Gerontology*, *163*, 111804. [https://doi.org/10.1016/j.exger.2022.111804](https://doi.org/10.1016/j.exger.2022.111804)
25. Meng, F., Fleming, B. A., Jia, X., Rousek, A. A., Mulvey, M. A., &amp; Ward, D. M. (2022). Lysosomal iron recycling in mouse macrophages is dependent upon both LcytB and Steap3 reductases. *Blood Advances*, *6*(6), 1692–1707. [https://doi.org/10.1182/bloodadvances.2021005609](https://doi.org/10.1182/bloodadvances.2021005609)
26. Nicholson, R. J., Poss, A. M., Maschek, J. A., Cox, J. E., Hopkins, P. N., Hunt, S. C., Playdon, M. C., Holland, W. L., &amp; Summers, S. A. (2021). Characterizing a Common CERS2 Polymorphism in a Mouse Model of Metabolic Disease and in Subjects from the Utah CAD Study. *The Journal of Clinical Endocrinology &amp; Metabolism*, *106*(8), e3098–e3109. [https://doi.org/10.1210/clinem/dgab155](https://doi.org/10.1210/clinem/dgab155)
27. Nie, X., Munyoki, S. K., Sukhwani, M., Schmid, N., Missel, A., Emery, B. R., DonorConnect, Stukenborg, J.-B., Mayerhofer, A., Orwig, K. E., Aston, K. I., Hotaling, J. M., Cairns, B. R., &amp; Guo, J. (2022). Single-cell analysis of human testis aging and correlation with elevated body mass index. *Developmental Cell*, *57*(9), 1160-1176.e5. [https://doi.org/10.1016/j.devcel.2022.04.004](https://doi.org/10.1016/j.devcel.2022.04.004)
28. Okada, M., Rajaram, K., Swift, R. P., Mixon, A., Maschek, J. A., Prigge, S. T., &amp; Sigala, P. A. (2022). Critical role for isoprenoids in apicoplast biogenesis by malaria parasites. *eLife*, *11*, e73208. [https://doi.org/10.7554/eLife.73208](https://doi.org/10.7554/eLife.73208)
29. Ost, K. S., O’Meara, T. R., Stephens, W. Z., Chiaro, T., Zhou, H., Penman, J., Bell, R., Catanzaro, J. R., Song, D., Singh, S., Call, D. H., Hwang-Wong, E., Hanson, K. E., Valentine, J. F., Christensen, K. A., O’Connell, R. M., Cormack, B., Ibrahim, A. S., Palm, N. W., … Round, J. L. (2021). Adaptive immunity induces mutualism between commensal eukaryotes. *Nature*, *596*(7870), 114–118. [https://doi.org/10.1038/s41586-021-03722-w](https://doi.org/10.1038/s41586-021-03722-w)
30. Øvrebø, J. I., Bradley-Gill, M.-R., Zielke, N., Kim, M., Marchetti, M., Bohlen, J., Lewis, M., van Straaten, M., Moon, N.-S., &amp; Edgar, B. A. (2022). Translational control of E2f1 regulates the Drosophila cell cycle. *Proceedings of the National Academy of Sciences*, *119*(4), e2113704119. [https://doi.org/10.1073/pnas.2113704119](https://doi.org/10.1073/pnas.2113704119)
31. Petrocelli, J. J., Mahmassani, Z. S., Fix, D. K., Montgomery, J. A., Reidy, P. T., McKenzie, A. I., de Hart, N. M., Ferrara, P. J., Kelley, J. J., Eshima, H., Funai, K., &amp; Drummond, M. J. (2021). Metformin and leucine increase satellite cells and collagen remodeling during disuse and recovery in aged muscle. *The FASEB Journal*, *35*(9), e21862. [https://doi.org/10.1096/fj.202100883R](https://doi.org/10.1096/fj.202100883R)
32. Rheinemann, L., Downhour, D. M., Bredbenner, K., Mercenne, G., Davenport, K. A., Schmitt, P. T., Necessary, C. R., McCullough, J., Schmitt, A. P., Simon, S. M., Sundquist, W. I., &amp; Elde, N. C. (2021). RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis. *Cell*, *184*(21), 5419-5431.e16. [https://doi.org/10.1016/j.cell.2021.09.008](https://doi.org/10.1016/j.cell.2021.09.008)
33. Tamamouna, V., Rahman, M. M., Petersson, M., Charalambous, I., Kux, K., Mainor, H., Bolender, V., Isbilir, B., Edgar, B. A., &amp; Pitsouli, C. (2021). Remodelling of oxygen-transporting tracheoles drives intestinal regeneration and tumorigenesis in Drosophila. *Nature Cell Biology*, *23*(5), Article 5. [https://doi.org/10.1038/s41556-021-00674-1](https://doi.org/10.1038/s41556-021-00674-1)
34. Van Deren, D. A., De, S., Xu, B., Eschenbacher, K. M., Zhang, S., &amp; Capecchi, M. R. (2022). Defining the Hoxb8 cell lineage during murine definitive hematopoiesis. *Development*, *149*(8), dev200200. [https://doi.org/10.1242/dev.200200](https://doi.org/10.1242/dev.200200)
35. Wojtalewicz, S., Vizmeg, J., Erickson, S., Lade, C., Shea, J., Sant, H., Magda, J., Gale, B., Agarwal, J., &amp; Davis, B. (2022). Evaluating the influence of particle morphology and density on the viscosity and injectability of a novel long-acting local anesthetic suspension. *Journal of Biomaterials Applications*, 8853282221106486. [https://doi.org/10.1177/08853282221106486](https://doi.org/10.1177/08853282221106486)
36. Xue, Q., Varady, S. R. S., Waddell, T. Q. A., Carrington, J., &amp; Roh-Johnson, M. (2022). *Focal adhesion-based cell migration is differentially regulated in vivo versus in vitro by Paxillin phosphorylation*. bioRxiv. [https://doi.org/10.1101/2022.03.02.482703](https://doi.org/10.1101/2022.03.02.482703)
37. Yang, G., Parker, E., Gorsi, B., Liebowitz, M., Maguire, C., King, J. B., Coon, H., Lopez-Larson, M., Anderson, J., Yandell, M., &amp; Shcheglovitov, A. (2022). *Neurite outgrowth deficits caused by rare PLXNB1 mutation in pediatric bipolar disorder* \[Preprint\]. Psychiatry and Clinical Psychology. [https://doi.org/10.1101/2022.05.06.22274499](https://doi.org/10.1101/2022.05.06.22274499)
38. Zhang, P., Katzaroff, A. J., Buttitta, L. A., Ma, Y., Jiang, H., Nickerson, D. W., Øvrebø, J. I., &amp; Edgar, B. A. (2021). The Krüppel-like factor Cabut has cell cycle regulatory properties similar to E2F1. *Proceedings of the National Academy of Sciences of the United States of America*, *118*(7), e2015675118. [https://doi.org/10.1073/pnas.2015675118](https://doi.org/10.1073/pnas.2015675118)
39. Zhao, H., Pomicter, A. D., Eiring, A. M., Franzini, A., Ahmann, J., Hwang, J.-Y., Senina, A., Helton, B., Iyer, S., Yan, D., Khorashad, J. S., Zabriskie, M. S., Agarwal, A., Redwine, H. M., Bowler, A. D., Clair, P. M., McWeeney, S. K., Druker, B. J., Tyner, J. W., … Deininger, M. W. (2022). MS4A3 promotes differentiation in chronic myeloid leukemia by enhancing common β-chain cytokine receptor endocytosis. *Blood*, *139*(5), 761–778. [https://doi.org/10.1182/blood.2021011802](https://doi.org/10.1182/blood.2021011802)

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